Polymer Micro- and Nano-Engineering/Micro- and Nanofluidics/Biomems and nems




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НазваниеPolymer Micro- and Nano-Engineering/Micro- and Nanofluidics/Biomems and nems
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Дата конвертации05.11.2012
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Publications


Polymer Micro- and Nano-Engineering/Micro- and Nanofluidics/BioMEMS and NEMS

1. X. Cao, S. Lai and L.J. Lee, “Design of a Self-Regulated Drug Delivery Device”, Biomedical Microdevices, 3(2), 109-118 (2001).


2. M.J. Madou, L.J. Lee, S. Daunert, K.W. Koelling, S. Lai, and C-H Shih, “Design and Fabrication of CD-like Microfluidic Platforms for Diagnostics, Part I: Microfluidic Functions”, Biomedical Microdevices, 3(3), 245-254 (2001).


3. L.J. Lee, M.J. Madou, K.W. Koelling, S. Daunert, S. Lai, C.G. Koh, Y-J Juang, Y. Lu and L Yu, “Design and Fabrication of CD-like Microfluidic Platforms for Diagnostics, Part II: Polymer-Based Microfabrication”, Biomedical Microdevices, 3(4), 339-351 (2001).


4. M.J. Madou, Y. Lu, S. Lai, C.G. Koh, L.J. Lee and B.R. Wenner, "A Novel Design on a CD Disc for 2-Point Calibration Measurement," Sensors and Actuators A, 91(3), 301-306 (2001).


5. Y-J Juang, L.J. Lee and K.W. Koelling, “Hot Embossing of Polymers for Microfabrication, Part I. Experimental”, Polymer Engineering & Science, 42(3), 539-550 (2002).


6. Y-J Juang, L.J. Lee and K.W. Koelling, “Hot Embossing of Polymers for Microfabrication, Part II. Rheological Characterization and Process Analysis”, Polymer Engineering & Science, 42(3), 551-566 (2002).


7. L. Yu, C.G. Koh, L.J. Lee, K.W. Koelling, and M.J. Madou “Experimental Investigation and Numerical Simulation of Injection Molding with Micro-Features”, Polymer Engineering & Science, 42(5), 871-888 (2002).


8. L.J. Lee, “BioMEMS and Micro-/Nano-Processing of Polymers- An Overview”, Journal of the Chinese Institute of Chemical Engineers, 34(1), 25-46 (2003).


9. S. Lai, S. Wang, L.J. Lee, S.T. Yang and M.J. Madou, “Design of a CD-like Microfluidic Platform for Enyzme-Linked Immunosobent Assay”, Analytical Chemistry, 76(7), 1832-1837 (2004).


10. S. Lai, X. Cao and L.J. Lee, “A Packaging Technique for Polymer Microfluidic Platforms”, Analytical Chemistry, 76, 1175-1183 (2004).


11. Y. Yang, C. Zeng and L.J. Lee, “Three-Dimensional Assembly of Polymer Microstructures at Low Temperatures”, Advanced Materials, 16(6), 560-564 (2004).


12. H. He, X. Cao and L.J. Lee, ”Design of a Hydrogel Based Intelligent System for Controlled Drug Release”, Journal of Controlled Release, 95(3), 391-402 (2004).


13. L. Yu, L.J. Lee and K.W. Koelling, “Flow and Heat Transfer Simulation of Injection Molding with Microstructures”, Polymer Engineering & Science, 44(10), 1866-1876 (2004).


14. Y. Yang, X. Hu, L.J. Lee and K.W. Koelling, “Investigation of Structure Evolution in Polymer Blending Using Microfabricated Samples”, Polymer, 45(6), 1959-1969 (2004).


15. Y-J. Juang, S. Wang, X. Hu and L.J. Lee, “Dynamics of Single Polymers in a Stagnation Flow Induced by Electrokinetics”, Physical Review Letters, 93, 268105 (2004). {selected for the January 10, 2005 issue of Virtual Journal of Nanoscale Science & Technology, Volume 11, Issue 1.}{selected for the January 1, 2005 issue of Virtual Journal of Biological Physics Research, Volume 9, Issue 1.}


16. Y. Yang, S. Basu, D.L. Tomasko, L.J. Lee and S.T. Yang, “Fabrication of Well-defined PLGA Scaffolds Using Novel Microembossing and Carbon Dioxide Bonding”, Biomaterials, 26(15), 2585-2594 (2005).


17. K. Kang, K.W. Koelling and L.J. Lee, “High Shear Microfluidics and Its Application in Rheological Measurement”, Experiments in Fluids, 38, 222-232 (2005).


18. S. Wang, C. Zeng, S. Lai, Y.J. Juang, Y. Yang and L.J. Lee, “Polymeric Nanonozzle Array Fabricated by Sacrificial Template Imprinting”, Advanced Materials, 17, 1182-1186 (2005).


****19. C. Lu, Y-J. Juang, L.J. Lee, D. Grewell and A. Benatar, “Analysis of Laser/IR-Assisted Micro-embossing”, Polymer Engineering & Science, 45(5), 661-668 (2005).


20. G. Xu, L. Yu, L.J. Lee and K.W. Koelling, “Experimental and Numerical Studies of Injection Molding with Microfeatures”, Polymer Engineering & Science, 45, 866-875 (2005).


21. Y. Yang, L.J. Lee, and W. Lu, "Subcritical Carbon Dioxide Assisted Polymer Nanofabrication at Low Temperatures", Journal of Vacuum Science and Technology B, 23(6), 3202 (2005) {selected for the December 19, 2005 issue of Virtual Journal of Nanoscale Science & Technology}.


22. C. Zeng, S. Wang, and L.J. Lee, "Dynamic Assembly of Silica for Fabrication of Nanoscale Polymer Channels", Materials Letters, 59, 3095-3098 (2005).


23. L. Li and L.J. Lee "Photopolymerization of HEMA/DEGDMA Hydrogels in Solution", Polymer, 46(25), 11540-11547 (2005).


24. J. Guan, H. He, L.J. Lee and D.J. Hansford, “Self-Folding of Hydrogel Three Dimensional Microstructures”, Journal of Physical Chemistry B: Condensed Matter, Materials Surfaces, Interfaces, and Biophysics, 109(49), 23134-23137 (2005).


25. Y-J Juang, S. Wang, C. Lu and L.J. Lee, “Electrokinetic Interactions in Microscale Flow Dynamics”, Applied Physical Letters, 87, 244105 (2005) {selected for the December 15, 2005 issue of Virtual Journal of Biological Physics Research, and the December 26, 2005 issue of Virtual Journal of Nanoscale Science & Technology}.


26. J. Guan and L. J. Lee, “Generating Highly Ordered and Stretched DNA Arrays”, Proceedings of National Academy of Science, 102(51), 18321-18325 (2005).


27. X. Hu, Z. Ding and L.J. Lee, “Simulation of 2D Transient Viscoelastic Flow Using the CONFESSIT Approach”, Journal of Non-Newtonian Fluid Mechanics, 127, 107-122 (2005).


28. L.J. Lee, “Polymer Nanoengineering for Biomedical Applications", Annals of Biomedical Engineering, (34)1, 75-88 (2006).


29. H. He, J. Guan, L.J. Lee and D.J. Hansford, "An Oral Delivery Device Based on Self-Folding Hydrogels", Journal of Controlled Release, 110, 339-346 (2006).


30. H. He, L. Li and L. J. Lee, “Photopolymerization and Structure Formation of Methacrylic Acid Based Hydrogels in Water/Ethanol Mixture”, Polymer, 47, 1612-1619 (2006).


31. K. Kang, L.J. Lee and K.W. Koelling, “Microdevice End Pressure Evaluations with Bagley Correction", Microfluidics and Nanofluidics, 2(3), 223-235 (2006).


32. J. Guan, N. Ferrell, L.J. Lee and D.J. Hansford, “"Fabrication of Polymeric Microparticles for Drug Delivery by Soft Lithography," Biomaterials, 27, 4034-4041 (2006).


33. X. Hu, S. Wang, Y-J Juang and L.J. Lee, “Five-cross Microfluidic Network Design Free of Coupling between Electrophoretic Motion and Electro-osmotic Flow”, Applied Physical Letters, 89, 084101 (2006) {selected for the September 4, 2006 issue of Virtual Journal of Nanoscale Science & Technology}.


34. Y. Bai, C. G. Koh, M. Boreman, Y-J Juang, I-C Tang, L.J. Lee, and S-T Yang, “Surface Modification for Enhancing Antibody Binding on Polymer-Based Microfluidic Device for Enzyme-Linked Immunosorbent Assay”, Langmuir; 22(22), 9458 – 9467 (2006).


35. H.C. Jung, W. Lu, S. Wang, L.J. Lee, and X. Hu, "Etching of Pyrex Glass Substrates by ICP-RIE for Micro/Nanofluidic Devices", Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures, 24(6), 3162-3164 (2006).


36. D.F. Farson, H.W. Choi, C. Lu, and L.J. Lee, “Femtosecond laser bulk micromachining of microfluid channels in poly(methyl methacrylate)”, Journal of Laser Applications, 18(3), 210-215, (2006).


37. Y. Yang, Y. Xie, X. Kang, L.J. Lee and D.A. Kniss, “Assembly of 3D Cell-Scaffold Constructs Using Carbon Dioxide”, Journal of American Chemistry Society, 128(43), 14040-14041 (2006).


^38. Y. Yang, D. Liu, L.J. Lee, and D.L. Tomasko, “Low Temperature Fusion of Polymeric Nanostructures Using Carbon Dioxide”, Advanced Materials, 19(2), 251-254 (2007).


39. Y. Yang, M-C Cheng, X. Hu, L.J. Lee, R. Goyette, and M. Ferrari, “CO2 Enhanced Polymer Surface Dynamics below the Bulk Glass Transition Temperature”, Macromolecules, 40(4), 1108-1111 (2007).


40. X. Kang, Y. Xie, H.M. Powell, L.J. Lee, M.A. Belury, J.J. Lannutti and D.A. Kniss, “Adipogenesis of Murine Embryonic Stem Cells in a Three-Dimensional Culture System Using Electrospun Polymer Scaffolds”, Biomaterials, 28(3), 450-458 (2007).


41. S. Wang and L.J. Lee, “Electrokinetically Assisted Dynamic Assembly in Microfluidics”, Journal of American Chemistry Society, 127(2), 254-255 (2007).


42. C. Lu, Y. Xie, M-C Cheng, Y. Yang, C-G Koh, L.J. Lee and Y-J Juang, “New Valving and Bonding Methods for Microfluidic Biochips Containing Proteins”, Analytical Chemistry, 79(3), 994-1001 (2007).


43. T.B. Stachowiak, D.A. Mair, T. G. Holden, L.J. Lee, F. Svec and J.M.J. Fréchet, “Hydrophilic Surface Modification of Cyclic Olefin Copolymer Microfluidic Chips Using Sequential Photografting”, J. Separation Science, 30, 1088-1093 (2007).


44. J. Guan, B. Yu and L.J. Lee, “Forming Highly Ordered Arrays of Functionalized Polymer Nanowires by Dewetting on Micropillars”, Advanced Materials, 19, 1212-1217 (2007).


45. C. Lu, M-C Cheng, A. Benatar and L.J. Lee, “Embossing of High-Aspect-Ratio-Microstructures Using Sacrificial Templates and Fast Surface Heating”, Polymer Engineering & Science, 47(6), 830-840 (2007).


46. J. Guan, H. He, L.J. Lee and D.J. Hansford, “Fabrication of Particulate Reservoir-Containing, Capsule-Like, and Self-Foldable Polymer Microstructures for Drug Delivery”, Small, 3, 412-418 (2007).


47. N-R Chiou, C. Lu, J. Guan, L.J. Lee and A.J. Epstein, “Growth and Alignment of Polyaniline Nanofibres with Superhydrophobic, Superhydrophilic and Other Properties”, Nature Nanotechnology, 2, 354-357 (2007).


48. Z. Fei, S. Wang, Y. Xie, B. Henslee and L.J. Lee, “Transgene Delivery to Mammalia Cells Using Membrane Sandwiched Electroporation’, Analytical Chemistry, 79(15), 5719-5722 (2007).


49. N-R Chiou, L.J. Lee and A.J. Epstein, “Self-assembled Polyaniline Nanofibers/Nanotubes”, Chemistry of Materials, 19, 3589-3591 (2007).


50. N-R. Chiou, C. Lu, J. Guan, L.J. Lee, A.J. Epstein, “Synthesis and Applications of Aligned Polyaniline and Polypyrrole Nanofibers”, Polymer Preprints, 48, 121-122, (2007).


51. J. Guan, N. Ferrell, B. Yu, D.J. Hansford and L.J. Lee, “Simultaneous Fabrication of Hybrid Arrays of Nanowires and Micro/Nanoparticles by Dewetting on Micropillars”, Soft Matter, 3(11), 1369-1371 (2007).


52. H. He, L. Li and L.J. Lee, "Photopolymerization and Structure Formation of Methacrylic Acid Based Hydrogels: the Effect of Light Intensity", Reactive and Functional Polymers, 68(1), 103-113 (2007).

53. X. Pan, J. Guan, J-W Yoo, A.J. Epstein, L.J. Lee and R.J. Lee, “Cationic Lipid Coated Magnetic Nanoparticles Associated with Transferrin for Gene Delivery”, International Journal of Pharmaceutics, 358, 263-270 (2008).

54. P. Pradhan, J. Guan, D. Lu, P. G. Wang, L.J. Lee and R.J. Lee, “A Facile Microfluidic Method for Production of Liposomes”, Anticancer Research, 28, 943-948 (2008).


55. R. Lapalombella, X. Zhao, G. Triantafillou, B. Yu, Y. Lin, G. Lozanski, C. Cheney, N. Heerema, D. Jarjoura, A. Lehman, L.J. Lee, R. Lee , M.A. Caligiuri, N. Muthusamy and J.C. Byrd, “A Novel Raji-Burkitt’s Lymphoma Model for Preclinical and Mechanistic Evaluation of CD52-Targeted Immunotherapeutic Agents”, Clinical Cancer Research, 14, 569-578 (2008).


56. N-R. Chiou, L.J. Lee, A.J. Epstein, “Porous Membrane Controlled Polymerization of Nanofibers of Polyaniline and Its Derivatives”, Journal of Materials Chemistry, 18, 2085-2089 (2008).


57. S. Wang and L.J. Lee, “Flow Guided Dynamic Assembly”, ChemPhysChem, 9, 967-973 (2008).


58. S. Wang, X. Hu and L.J. Lee "Electrokinetics Induced Asymmetric Transport in Polymeric Nanonozzles", Lab on a Chip, 8, 573-581 (2008).


59. K. Park, J. Jang, D. Irimia, J. Sturgis, L.J. Lee, P. Robinson, M. Toner and R. Bashir, “Living Cantilever Arrays for Characterization of Mass of Single Live Cells in Fluids”, Lab on a Chip, 8, 1034-1041 (2008).


60. X. Zhang, H. He and L.J. Lee, “A Biodegradable, Immunoprotective, Dual Nanoporous Capsule for Cell-Based Therapies”, Biomaterials, 29, 4253-4259 (2008).


61. R. Lapalombella, B. Yu, G. Triantafillou, Q. Liu, G. Lozanski, A. Ramanunni, L. Smith, W. Blum, L. Andritsos, D-S Wang, A. Lehman, C-S Chen, A. Johnson, G. Marcucci, R. Lee, L.J. Lee, N. Muthusamy and J.C. Byrd, “Lenalidomide Down-Regulates the CD20 Antigen and Antagonizes both Direct, Complement, and Antibody Dependent Cellular Cytotoxicity of Rituximab on Primary Chronic Lymphocytic Leukemia Cells”, Blood, 112(13), 5180-5189 (2008).


62. A. Yi, D.F. Farson, W. Lu and L.J. Lee, “Overview of Polymer Micro/Nanofabrication for Biomedical Applications”, Advances in Polymer Technology, 27(4), 188-198 (2008).


63. X. Yang, C.G. Koh, S. Liu, X. Pan, R. Santhanam, B. Yu, Y. Peng, J. Pang, S. Golan, Y. Talmon, Y. Jin, N. Muthusamy, J.C. Byrd, K.K. Chan, L.J. Lee, G. Marcucci and R.J. Lee, “Transferrin Receptor-Targeted Lipid Nanoparticles for Delivery of an Antisense Oligodeoxyribonucleotide against Bcl-2”, Molecular Pharmaceutics, 6, 221-230 (2009).


64. Y. Yuan, H. He, and L.J. Lee, “Protein A-based Immobilization of Antibody onto A Polymeric Microfluidic Device for Enzyme-linked Immunosorbent Assay”, Bioengineering and Biotechnology, 102(3), 891-901 (2009).


65. X. Yang, X. Zhao, M.A. Phelps, L. Piao, Q. Liu, D.M. Rozewski, L.J. Lee, G. Marcucci, M.R. Grever, J.C. Byrd, J.T. Dalton and R.J. Lee, “A Novel Liposomal Formulation of Flavopiridol”, International Journal of Pharmaceutics, 365, 170-174 (2009).


66. G. Zhai, J. Wu, G. Xiang, W. Mao, B. Yu, H. Li, L. Piao, L.J. Lee and R.J. Lee, “A Folate Receptor-Targeted Liposomal Formulation for Docetaxel Delivery”, Journal of Nanoscience and Nanotechnology, 9, 2155-2161 (2009).


67. H. He, Y. Yuan, W. Wang, N-R Chiou and L.J. Lee, “Design and Testing of a Microfluidic Biochip for Cytokine Enzyme-Linked Immunosorbent Assay (ELISA)”, Biomicrofluidics, 3, 022401 (2009). April 15, 2009 issue of Virtual Journal of Biological Physics Research


68. B. Yu, X. Zhao, L.J. Lee and R.J. Lee, “Targeted Delivery Systems for Oligonucleotide Therapeutics”, American Association of Pharmaceutical Scientists Journal, 11(1), 195-203 (2009).


69. X. Hu, S. Wang and L.J. Lee, “"Single-Molecule DNA Dynamics in Tapering Contraction-Expansion Microchannels under Electrophoresis", Journal of Physics Review E, 79, 041911 (2009).


70. Y. Xie, Y. Yang, X. Kang, L.J. Lee, and D.A. Kniss, “Assembly of Embryonic Stem Cell/Scaffold Three-Dimensional Constructs Using Carbon Dioxide Assisted Polymer Fusion”, Biotechnology Progress, 25(2), 535-542 (2009).


71. C-H Lin, J. Guan, S-W Chau and L.J. Lee, “Experimental and Numerical Analysis of DNA Nanowire Array Formation by Surface Patterned Molecular Combing”, Journal of Physics D: Applied Physics, 42, 02503 (2009).


72. X. Zhang, Y. Xie, C-G Koh and L. J. Lee, “A Novel 3-D Model for Cell Culture and Tissue Engineering”, Biomedical Microdevices, 11, 795-799 (2009).


73. X. Zhang, C.G. Koh, B. Yu, S. Liu, L. Piao, G. Marcucci, R.J. Lee and L.J. Lee, “Transferrin Receptor Targeted Lipopolyplexes for Delivery of Antisense Oligonucleotide G3139 in a Murine K562 Xenograft Model”, Pharmaceutical Research, 26(6), 1516-1524 (2009).


74. J. Yang, C. Liu, Y. Yang, B. Zhu, L.J. Lee, H. Chen and Y.C. Jean „Analysis of Polystyrene Surface Properties Using Nanoparticle Embedding Technique”, Journal of Polymer Science, Part B: Polymer Physics, 47, 1535-1542 (2009).


75. S. Wang, X. Zhang, W. Wang, and L.J. Lee, “Semi-continuous Flow Electroporation Chip for High Throughput Transfection on Mammalian Cells”, Analytical Chemistry, 81, 4414-4421 (2009).


76. C.G. Koh, X. Kang, Z. Fei, J. Guan, Y. Xie, B. Yu and L.J. Lee, “Assembly of PEI/DNA Nanoparticles for Gene Delivery by Microfluidic Hydrodynamic Focusing”, Molecular Pharmaceutics, 6(5), 1333-1342 (2009).


77. Y. Wu, B. Yu, A. Jackson, W. Zha, L.J. Lee, B.E. Wyslouzil, “Electrohydrodynamic Spraying: A Novel One-Step Technique to Prepare Oligodeoxynucleotide (ODN) Encapsulated Lipoplex Nanoparticles”, Molecular Pharmaceutics,, 6(5), 1371-1379 (2009).


78. C. Yen, H. He, W. Ho, and L.J. Lee, " Synthesis and Characterization of Nanoporous Polycaprolactone Membranes via Thermally- and Nonsolvent-Induced Phase Separations for Biomedical Device Applications”, J. Membrane Science, 343, 180-188 (2009).


79. X. Wen, H. He and L.J. Lee, “Antibody Immobilization with Biotin-Derivatized Poly(L-lysine)-g-Poly(ethylene glycol) on Polymeric Microfluidic Chips for Enzyme-Linked Immunosorbent Assay”, Journal of Immunology Methods, 350, 97-105 (2009).


80. W. Weecharangsan, B. Yu, Y. Zheng, S. Liu, J. Pang, L.J. Lee, G. Marcucci and R. Lee, "Efficient Delivery of Antisense Oligodeoxyribonucleotide G3139 by Human Serum Albumin-coated Liposomes", Molecular Pharmaceutics, 6, 1848-1855 (2009).


81. C.G. Koh, X. Zhang, S. Liu, S. Golan, B. Yu, X. Yang, J. Guan, Y. Jin, Y. Talmon, R. Muthasamy, K.K Chan, J. Bryd, R.J. Lee, G. Marcucci and L.J. Lee, “Delivery of Antisense Oligodeoxyribonucleotide Lipopolyplex Nanoparticles Assembled by Microfluidic Hydrodynamic Focusing”, Journal of Controlled Release, 141, 62-69 (2010).


82. Y. Jin, B. Yu, S. Liu, L.J. Lee, R. Lee and G. Marcucci, “Transferrin Mediated Targeted Delivery of GTI-2040 into Acute Myeloid Leukemia (AML) By pH-Sensitive Lipopolyplex Nanoparticles”, Molecular Pharmaceutics, 7(1), 196-206 (2010).


83. Z. Fei, X. Hu, H. Choi, D. Farson and L. J. Lee, "Micro-nozzle Array Enhanced Sandwich Electroporation of Embryonic Stem Cells", Analytical Chemistry, 82(1), 351-358 (2010).


84. L. Lei, C. Yang, H. Shi, W-C Liao, H. Huang, L.J. Lee, J. Castro and A. Yi, "Design and Fabrication of an Affordable Polymer Micromixer for Medical and Biomedical Applications", Polymer Engineering and Science, 50, 1594-1604 (2010).


85. L.B. Zimmerman, M.D. Rauscher, J. Ellis, P. Poukany and L.J. Lee, “Nanoimprinting Using Self-assembled Ceramic Nanoislands”, Nanotechnology, 21(4), 045304 (2010).


86.Y. Wu, Z. Fei, L.J. Lee and B.E. Wyslouzil, “Coaxial Electro-hydrodynamic Spraying of Plasmid DNA/Polyethylenimine (PEI) for Nonviral Gene Delivery”, Biotech. Bioeng., 105, 834 -841 (2010).


87. P. Boukany, O. Hemminger, S-Q Wang and L.J. Lee, “Molecular Imaging of Slip in Entangled DNA Solution”, Physical Review Letters, 105(2), 027802 (2010).


88. D. G. Perez; N. Higuita-Castro; S. Sharma; R. Reen; A. F. Palmer; K. Gooch; L.J. Lee; J. Lannutti and D. Hansford, “High Throughput Assembly of Spatially Controlled 3D Cell Clusters on a Micro/Nano Platform”, Lab on a Chip, 10, 775-782 (2010).


89. Y. Zheng, B. Yu, W. Weecharangsan, L. Piao, M. Darby, Y. Mao, R. Koynova, X. Yang, H. Li, S. Xu, L.J. Lee, Y. Sugimotoc, R.W. Brueggemeier, R.J. Lee, “ Transferrin Conjugated Lipid-coated PLGA Nanoparticles for Targeted Delivery of Aromatase Inhibitor 7α-APTADD to Breast Cancer Cells”, International Journal of Pharmaceutics, 390(2), 234-241 (2010).


90. W. Weecharangsan, B. Yu, S. Liu, J. Pang, L.J. Lee, G. Marcucci and R.J. Lee, “Bioreversible Disulfide-linked Liposomes: Effective Delivery Vehicle for Bcl-2 Antisense Oligodeoxyribonucleotide G3139.”, Anticancer Res., 30, 31-38 (2010).


91. C. Zhou, B. Yu, X. Yang, T. Huo, L.J. Lee, R.F. Barth and R.J. Lee, “Lipid-coated Nano-calcium-phosphate (LNCP) for Gene Delivery”, International Journal of Pharmaceutics, 392, 201-208 (2010).


92. X. Huang, R. Caddell, B. Yu, S. Xu, B. Theobald, L.J. Lee and R.J. Lee, “Ultrasound-enhanced Microfluidic Synthesis of Liposomes.”, Anticancer Res., 30, 463-466 (2010).


93. C. Yen, H. He, Z. Fei, X. Zhang, L.J. Lee, and W.S. Ho, "Surface Modification of Nanoporous Poly( -caprolactone) Membrane with Poly(ethylene glycol) to Prevent Biofouling: Part I. Effects of Plasma Power and Treatment Time", International Journal of Polymeric Materials, 59(11), 923-942 (2010).

94. C. Yen, H. He, Z. Fei, X. Zhang, L.J. Lee, and W.S. Ho, "Surface Modification of Nanoporous Poly( -caprolactone) Membrane with Poly(ethylene glycol) to Prevent Biofouling: Part II. Effects of Graft Density and Chain Length", International Journal of Polymeric Materials, 59(11), 943-957 (2010).


95. J. Guan, P.E. Boukany, N-R Chiou, O. Hemminger, W. Zha, M. Cavanaugh and L.J. Lee, “Laterally Ordered Nanochannel Arrays from DNA Combing and Imprinting”, Advanced Materials, 22, 3997-4001 (2010).


96. S. Wang, X. Zhang, B. Yu, R.J. Lee and L.J. Lee, “Targeted Nanoparticles Enhanced Flow Electroporation of Antisense Oligonucleotides in Leukemia Cells”, Biosensors and Bioelectronics, 26(2), 778-783 (2010).


97. J. Xu, K.J. Kwak, L.J. Lee and G. Agarwal, “Lifting and Sorting of Charged Au Nanoparticles by Electrostatic Forces in Atomic Force Microscopy”, Small, 6(19), 2105-2108 (2010).


98. A. Srivastava, Y. Yang, L.J. Lee and S. Ghosh, “Molecular Dynamics Simulations and Experimental Validation of Glass Transition Temperature of Polystyrene Thin Films under CO2 Pressure”, Modeling and Simulation in Materials Science and Engineering, 18(6), 65003-65024 (2010).


99. L. Li, L.J. Lee, J.M. Castro and A. Yi, "Improving Mixing Efficiency of A Polymer Micromixer by Use of A Plastic Shim Divider," Journal of Micromechanics and Microengineering, 20, 035012 (2010).


100. C H Lin, J Guan, S W Chau, L J Lee and S C Chen, “Experimental and Numerical Analysis of DNA Nanowire Array Formation by Molecular Combing on Micropillar-Patterned Surface”, Biomicrofluidics, 4, 034103, 1-15 (2010).


101. B. Yu, L.J. Lee and R.J. Lee, “Novel Receptor-targeted Drug Delivery Systems and Therapeutic Strategies”, Molecular Membrane Biology, 27(7), 286-298 (2010).


102. O. Hemminger, P. Boukany, X. Hu, S. Wang and L.J. Lee, “Flow Visualization of Viscoelastic Flow of Concentrated DNA Solutions through a Microscale 4:1 Planar Contraction Device”, Journal of Non-Newtonian Fluid Mechanics, 165, 1613-1624 (2010).


103. K.J. Kwak, G. Valincius, W-C Liao, X. Hu, X. Wen, A. Lee, B. Yu, W. Lu, D. Vanderah and L.J. Lee, “Formation and Analysis of Tethered Bilayer Lipid Structures”, Langmuir, 26(23), 18199-18208 (2010).


104. Y. Lim, J. Johnson, Z. Fei, Y. Wu, D. Farson, J.J. Lannutti, H. W. Choi and L.J. Lee, “Micropatterning and Characterization of Electrospun Poly(ε-caprolactone)/Gelatin Nanofiber Tissue Scaffolds by Femtosecond Laser Ablation for Tissue Engineering Applications”, Biotechnology & Bioengineering, 108 (1), 116-126 (2011).


105. H. He, V. Grignol, C. Yen, N.B. Jones, M.I. Liang, K.A. Varker, G.B. Lesinski, W. Ho, W.E. Carson, III and L.J. Lee, “Use of a Nanoporous Biodegradable Miniature Devices to Regulate Cytokins Release for Cancer Treatment”, Journal of Controlled Release, 151, 239-245 (2011).


106. X. Hu, P. Boukany, O. Hemminger and L.J. Lee, “The Use of Microfluidics in Rheology”, Macromolecular Materials and Engineering, 296, 308-320 (2011).


107. B. Yu, J. Zhu, W. Xue, Y. Wu, X. Huang, L.J. Lee and R.J. Lee, “Microfluidic Assembly of Lipid-Based Oligonucleotide Nanoparticles”, Anticancer Research Journal, 31, 771-776 (2011).


108. X. Yang, P. Yong, B, Yu, J. Yu, Y. Mao, C. Zhou, L.J. Lee and R.J. Lee, "A Covalently Stabilized Lipid-Polycation-DNA (sLPD) Vector for Antisense Oligonucleotide Delivery", Molecular Pharmaceutics, 8, 709-715 (2011).


109. B. Henslee, A. Morss, X. Hu, G. Lafyatis and L.J. Lee, “Threshold Fields for Electropermeabilization Are Measured To Be Independent of Cell Size”, Analytical Chemistry, 83, 3998-4003 (2011).


110. H. Li, L. Piao, B. Yung, B. Yu, G. Wang, L.J. Lee and R.J. Lee, “Efficient Delivery of Calf Thymus DAN to Tumor by Folate Receptor Targeted Cationic Liposomes”, Biomaterials, 32, 6614-6620 (2011).


111. X. Wang, B. Yu, Y. Wu, X. Zou, R.J. Lee and L.J. Lee, “Efficient Down-regulation of CDK4 by Novel Lipid Nanoparticle-mediated siRNA Delivery”, Anticancer Research Journal, 31, 1619-1626 (2011).


112. Y. Wu, Y-P Ho, Y. Mao, X. Wang, B. Yu, K.W. Leong and L.J. Lee, “Uptake and Intracellular Fate of Multifunctional Nanoparticles: a Comparison between Lipoplexes and Polyplexes via Quantum Dots-FRET”, Molecular Pharmaceutics, 9, ????-???? (2011).


113. Y. Wu, M. Crawford, B. Yu, Y. Mao, S. Nana-Sinkam and L.J. Lee, “MicroRNA Delivery by Cationic Lipoplexes for Lung Cancer Therapy", Molecular Pharmaceutics, 8, 1381-1389 (2011).


114. P. E. Boukany, A. Morss, W-C Liao, B. Henslee, X. Zhang, B. Yu, X. Wang, Y. Wu, H.C. Jung, L. Li, K. Gao, X. Hu, X. Zhao, O. Hemminger, W. Lu, G. Lafyatis and L.J. Lee, “Nanochannel Electroporation Delivers Precise Amounts of Biomolecules into Living Cells ”, Nature Nanotechnology, 6, 747-754 (2011), research highlight in Nature Methods, 8, 996-997 (2011).


115. C. Zhou, Y. Mao, Y. Sugimoto, N. Kanthamneni, B. Yu, R.W. Brueggemeier, L.J. Lee and R.J. Lee, “Surfactant Vesicles, SPANosomes as Delivery Vehicles for Small Interfering RNA (siRNA)”, Molecular Pharmaceutics, accepted.


116. Z. Fei, S. Sharma, Y. Wu, D. G. Perez, J.J. Lannutti, D. Hansford and L.J. Lee, “Gene Delivery by Membrane Sandwich Electroporation of Cells Incubated on Nanofiber Feeder Layer”, ACS Nano, accepted.


Polymer Nanocomposites/Foams/Supercritical CO2 Technology

  1. M. Elkovitch, D.L. Tomasko and L.J. Lee, “Supercritical CO2 Assisted Polymer Blending”, Polymer Engineering & Science, 39(10), 2075-2084 (1999).


2. M. Elkovitch, L. J. Lee and D.L. Tomasko, “Effect of Supercritical CO2 on Morphology Development in Polymer Blending”, Polymer Engineering & Science, 40, 1850-1861 (2000).


3. C. Zeng and L.J. Lee, “Poly(methyl methacrylate) and Polystyrene/Clay Nanocomposites Prepared by In-Situ Polymerization”, Macromolecules, 34, 4098-4103 (2001).


4. H. Wang, C. Zeng, M. Elkovitch, L.J. Lee and K.W. Koelling, “Processing and Properties of Polymeric Nano-composites”, Polymer Engineering & Science, 41(11), 2036-2046 (2001).


5. M. Elkovitch, L. J. Lee and D.L. Tomasko, “Effect of Supercritical CO2 on PMMA/Rubber and PS/Rubber Blending: Viscosity Ratio and Phase Inversion”, Polymer Engineering & Science, 41(12), 2108-2125 (2001).


6. X. Han, K.W. Koelling, D.L. Tomasko and L.J. Lee, “Continuous Microcellular Polystyrene Foam Extrusion with Supercritical CO2”, Polymer Engineering & Science, 42(11), 2094-2106 (2002).


7. P. Svoboda, C. Zeng, H. Wang, and L.J. Lee, “Morphology and Mechanical Properties of PP/Organoclay Nanocomposites”, Journal of Applied Polymer Science, 87, 1562-1570 (2002).


8. D.L. Tomasko, H. Li, D. Liu, X. Han, M.J. Wingert, L.J. Lee and K.W. Koelling, “A Review of CO2 Applications in the Processing of Polymers”, I&EC Research, 42(25), 6431-6456 (2003).


9. X. Han, C. Zeng, L.J. Lee, K.W. Koelling and D.L. Tomasko, “Extrusion of Polystyrene Nanocomposite Foams with Supercritical CO2”, Polymer Engineering & Science, 43(6), 1261-1275 (2003).


10. C. Zeng, X. Han, L.J. Lee, K.W. Koelling and D.L. Tomasko “Polymer/Clay Nanocomposite Foams Prepared Using CO2”, Advanced Materials, 15(20), 1743-1747 (2003).


11. D.L. Tomasko, X. Han, D. Liu, W. Gao, K.W. Koelling and L.J. Lee, “Supercritical Fluid Applications in Polymer Nanocomposites”, Current Opinion in Solid State & Materials Science, 8, 407-412 (2003).


12. H. Li, L.J. Lee and D.L. Tomasko, “Effect of Carbon Dioxide on the Interfacial Tension of Polymer Melts”, I&EC Research, 43, 509-514 (2004).


13. L. Xu and L.J. Lee, “Effect of Nanoclay on Shrinkage Control of Low Profile Unsaturated

Polyester (UP) Resin Cured at Room Temperature”, Polymer, 45(21), 7325-7334 (2004).


14. X. Cao, L. J. Lee, T. Widya, and C.W. Macosko, "Polyurethane/Clay Nanocomposites Foams: Processing, Structure and Properties", Polymer, 46, 775-783 (2005).


15. L. Xu and L.J. Lee, “Kinetic Analysis and Mechanical Properties of Nanoclay Reinforced Unsaturated Polyester (UP) Resins Cured at Low Temperatures" Polymer Engineering and Science, 45(4), 496-509 (2005).


16. J. Shen, C. Zeng and L.J. Lee, “Synthesis of Polystyrene-Carbon Nanofiber Microcellular Foams”, Polymer, 46, 5218-5224 (2005).


17. L.J. Lee, C. Zeng, X. Cao, X. Han, J. Shen and G. Xu, “Polymer Nanocomposite Foams”, Composite Science and Technology, 65(15-16), 2344-2363 (2005).


18. X. Han, L.J. Lee and D.L. Tomasko, “CO2 Foaming of Polymer Nanocomposite Blends”, Aust. J. Chem., 58, 492-503 (2005).


19. J. Shen, X. Han and L.J. Lee, “Nanoscaled Reinforcement of Polystyrene Foams using Carbon Nanofibers”, J. Cellular Plastics, 42(2), 105-126 (2006).


20. J. Shen, X. Cao and L.J. Lee, “Synthesis and Foaming of Water Expandable Polystyrene-Clay Nanocomposites’, Polymer, 47(18), 6303-6310 (2006).


21. X. Han, J. Shen, H. Huang and L.J. Lee, “CO2 Foaming Based on Polystyrene / Poly (methyl methacrylate) Blend and Nanoclay”, Polymer Engineering & Science, 47(2), 103-111 (2007).


22. G. Zhou, L.J. Lee and J. Castro, “Nanoclay and Long Fiber Reinforced Composites based on Epoxy and Phenolic Resins", Journal of Applied Polymer Science, 108 (6), 3720-3726 (2008).


23. Z. Guo, J. Yang, M.E. Berg, M.J. Wingert, D.L. Tomasko, L.J. Lee and T. Daniel, “Comparison of Carbon Nanofibers and Activated Carbon on Carbon Dioxide Foaming of Polystyrene”, Journal of Cellular Plastics, 44, 453-468 (2008).


24. H. Chen, M-L Cheng, Y.C. Jean, L.J. Lee and J. Yang, “Effect of CO2 Exposure on Free Volumes in Polystyrene Studied by Positron Annihilation Spectroscopy”, Journal of Polymer Science, Part B: Polymer Physics, 46, 388-405 (2008).


25. Y.C. Jean, H. Chen, L.J. Lee and J. Yang, “Positron Annihilation Lifetime and Glass Transition Temperatures in CO2 Sorption Polystyrene", Acta Physica Polonica, 113, 1385-1395 (2008).


26. V. Khanna, B. Bhakshi and L.J. Lee, “Carbon Nanofiber Production: Life Cycle Energy Consumption and Environmental Impact”, Journal of Industrial Ecology, 12(3), 394-410 (2008).


27. Z. Guo, L.J. Lee and D.L. Tomasko, "CO2 Permeability in Polymer Nanocomposites and Nanocomposite Foams", Industrial & Engineering Chemistry Research, 47(23), 9636-9643 (2008).


28. G. Zhou, S. Movva and L.J. Lee, “Preparation and Properties of Nanoparticle and Long Fiber Reinforced Unsaturated Polyester Composites”, Polymer Composites, 30(7), 861-865 (2009).


29. S. Movva, G. Zhou, D. Guerra, and L.J. Lee, “Effect of Carbon Nanofibers on Mold Filling in a Vacuum Assisted Resin Transfer Molding System”, J. Composite Materials, 43(6), 611-620 (2009).


30. Y.C. Jean, H.M. Chen, L.J. Lee, J. Yang, X. Gu, W.S. Hung, K.R. Lee, J.Y. Lai, Y.M. Sun and C.C. Hu, “Positronium Chemistry in Polymeric Membrane Systems”, Materials Science Forum, 607, 1-8 (2009).


31. H.M. Chen, L.J. Lee, J. Yang, X. Gu and Y.C. Jean, “Free Volumes in Polymer Nanocomposites”, Materials Science Forum, 607, 177-179 (2009).


32. J. Yang, S.K. Yeh, N.R. Chiou, Z. Guo, T. Daniel and L.J. Lee, “Synthesis and Foaming of Water Expandable Polystyrene-Activated Carbon Composites”, Polymer, 50, 3169-3173 (2009).


33. M.J. Wingert, S. Shukla, K.W. Koelling, D.L. Tomasko and L.J. Lee, “Shear Viscosity of CO2-Plastized Polystyrene under High Static Pressure”, I&EC Research, 48(11), 5460-5471 (2009).


34. Z. Guo; S.K. Yeh; M.J. Wingert, D.L.Tomasko and L.J. Lee, “Comparison of Carbon Nanofibers and Nanoclay on Rheology of Polystyrene under Supercritical Carbon Dioxide”, Journal of Applied Polymer Science, 116(2), 1068-1076 (2010).


35. B. Zhu, W. Zha, J. Yang, C. Zhang and L.J. Lee, “Layered-Silicate Based Polystyrene Nanocomposite Microcellular Foam Using Super Critical Carbon Dioxide as Blowing Agent”, Polymer, 51, 2177-2184 (2010).


36. S-K Yeh, J. Yang, N-R Chiou, T. Daniel and L.J. Lee, “Introducing Water as a Co-Blowing Agent in the Carbon Dioxide Extrusion Foaming Process for Polystyrene Thermal Insulation Foams”, Polymer Engineering and Science, 50, 1577-1584 (2010).


37. Z. Cai, S. Movva, N-R Chiou, J. Castro and L.J. Lee, "Effect of Polyaniline-Surface Modified Carbon Nanofibers on Cure Kinetics of Epoxy Resin", J. Applied Polymer Science, 118(4), 2328-2335 (2010).


38. S. Awad, H Chen, G. Chen, X. Gu, L.J. Lee, E.E. Abdel-Hady and Y.C. Jean, “Free Volumes, Glass Transitions and Cross-links of Zinc Oxide/Waterborne Polyurethane Nanocomposites”, Macromolecules, 44, 29-38 (2011).


39. C. Zhang, B. Zhu and L.J. Lee, “Extrusion Foaming of Polystyrene/Carbon Particles Using Carbon Dioxide and Water as Co-blowing Agents”, Polymer, 52, 1847-1855 (2011).


40. R. Mulyanal, E. Cabreral, J.M. Castro and L.J. Lee, “Injection Molding of Water Containing Thermoplastic Polyolefin”, International Polymer Processing, accepted.


41. A. Burley, Z. Gao, L.J. Lee, K.W. Koelling, I. Kusaka and D.L. Tomasko, “CO2 Bubble Nucleation in Polystyrene: Experimental and Modeling Studies”, J. Applied Polymer Science, accepted.


42. C. Zhang, B. Zhu and L.J. Lee, “Bimodal Polystyrene Foams Using Carbon Dioxide and Water as Co-blowing Agents”, submitted to Polymer.


43. S. Movva, D. Guerra, X. Ouyang, J. Castro and L.J. Lee “Cure Kinetics of Carbon Nanofiber/Vinyl Ester Nanocomposites at Low Temperature”, J. Applied Polymer Science, accepted


44. S. Movva, X. Ouyang, J. castro and L.J. Lee, “Carbon Nanofiber Paper and Its Effect on Cure Kinetics of Low Temperature Epoxy Resin”, POLYMER, accepted.


Reactive Processing and Thermoset Polymers
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